Avirulent Clostridium perfringens Strains Obtained by Euflavine Treatment

Avirulent Clostridium perfringens strains obtained by euflavine treatment.

Clostridium perfringens was incubated in the presence of euflavine (EU); the resistant mutants which were thus isolated had highly reduced capacity to release alpha-toxin. This fact was confirmed by lecithinase determinations and by immunoelectrophoresis. Injected into guinea pigs and into 6- to 7-day-old chicks, these mutants were completely avirulent. A study of their properties indicated bio...

Some Observations on Clostridium perfringens Strains Isolated in IRAN

some observations on clostridium perfringens strains isolated in iran

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Antitoxin treatment for liver abscess caused by Clostridium perfringens

We read with great interest the article ‘A case of emphysematous hepatitis with spontaneous pneumoperitoneum in a patient with hilar cholangiocarcinoma’ by Jung Ho Kim et al. The authors described fatal case of emphysematous hepatitis caused by C. perfringens , but did not mention the hemolysis or disseminated intravascular coagulopathy (DIC) during hospital course. Laboratory data on admission...

Distribution of neuraminidase among food-poisoning strains of Clostridium perfringens.

A survey was made to determine the distribution of the enzyme neuraminidase among 76 strains of Clostridium perfringens. Representative strains from each toxigenic type (A to F) and atypical C. perfringens type A food-poisoning strains of both American and English (Hobbs types) origin were tested. Both the American food-poisoning and nonfood-poisoning associated cultures consisted of both neura...